Abstract:Long video generation requires high-fidelity synthesis, coherent narrative structure, and user control over extended time spans. Existing text-to-video methods often rely on a single long prompt, limiting control over pose, composition, layout, and motion. We propose DrawVideo, a sketch-guided, storyboard-driven framework for controllable long-video generation. DrawVideo decomposes long videos into independently controllable shots, each defined by a black-and-white sketch, an appearance prompt, and a motion prompt. The sketch controls pose and layout, the appearance prompt defines identity, scene, and style, and the motion prompt guides temporal dynamics. DrawVideo follows a hierarchical 'global multi-shot, local single-sketch' strategy: it first generates a structure-aligned reference keyframe, then expands the motion prompt into derivative keyframes representing action states, and finally synthesizes clips between adjacent keyframes to build each shot. We also introduce SketchLongVideo, the first dataset for sketch-guided text-to-long-video generation, constructed from animation videos via shot detection, keyframe extraction, vision-language recognition, prompt decomposition, and sketch conversion. Experiments show that DrawVideo achieves strong structural controllability, appearance consistency, visual stability, and coherent long-video generation.
Abstract:Histopathology whole-slide images (WSIs) are routinely acquired in clinical practice and contain rich tissue morphology but lack direct molecular architecture and functional programs defining pathological states, whereas RNA sequencing (RNA-seq) provides genome-wide transcriptional profiles at substantial cost, thereby motivating WSI-based genome-wide transcriptomic prediction. Existing approaches for predicting gene expression from WSIs predominantly rely on deterministic regression with one-to-one mapping, limiting their ability to capture biological heterogeneity and predictive uncertainty. We propose RNA-FM, a flow-matching generative framework for genome-wide bulk RNA-seq prediction from WSIs. RNA-FM formulates transcriptomic prediction as a continuous-time conditional transport problem, learning a velocity field that maps a simple prior to the target gene expression distribution conditioned on morphologies. By integrating pathway-level structure, RNA-FM enables scalable and biologically interpretable genome-wide gene expression imputation. Extensive experiments demonstrate that RNA-FM consistently outperforms state-of-the-art approaches while maintaining biological meaningfulness. Code is available at https://github.com/YXSong000/RNA-FM.
Abstract:As 3D Gaussian Splatting (3DGS) gains attention in immersive media and digital content creation, assessing the aesthetics of 3D scenes becomes important in helping creators build more visually compelling 3D content. However, existing evaluation methods for 3D scenes primarily emphasize reconstruction fidelity and perceptual realism, largely overlooking higher-level aesthetic attributes such as composition, harmony, and visual appeal. This limitation comes from two key challenges: (1) the absence of general 3DGS datasets with aesthetic annotations, and (2) the intrinsic nature of 3DGS as a low-level primitive representation, which makes it difficult to capture high-level aesthetic features. To address these challenges, we propose Aes3D, the first systematic framework for assessing the aesthetics of 3D neural rendering scenes. Aes3D includes Aesthetic3D, the first dataset dedicated to 3D scene aesthetic assessment, built on our proposed annotation strategy for 3D scene aesthetics. In addition, we present Aes3DGSNet, a lightweight model that directly predicts scene-level aesthetic scores from 3DGS representations. Notably, our model operates solely on 3D Gaussian primitives, eliminating the need for rendering multi-view images and thus reducing computational cost and hardware requirements. Through aesthetics-supervised learning on multi-view 3DGS scene representations, Aes3DGSNet effectively captures high-level aesthetic cues and accurately regresses aesthetic scores. Experimental results demonstrate that our approach achieves strong performance while maintaining a lightweight design, establishing a new benchmark for 3D scene aesthetic assessment. Code and datasets will be made available in a future version.
Abstract:2D visual foundation models, such as DINOv3, a self-supervised model trained on large-scale natural images, have demonstrated strong zero-shot generalization, capturing both rich global context and fine-grained structural cues. However, an analogous 3D foundation model for downstream volumetric neuroimaging remains lacking, largely due to the challenges of 3D image acquisition and the scarcity of high-quality annotations. To address this gap, we propose to adapt the 2D visual representations learned by DINOv3 to a 3D biomedical segmentation model, enabling more data-efficient and morphologically faithful neuronal reconstruction. Specifically, we design an inflation-based adaptation strategy that inflates 2D filters into 3D operators, preserving semantic priors from DINOv3 while adapting to 3D neuronal volume patches. In addition, we introduce a topology-aware skeleton loss to explicitly enforce structural fidelity of graph-based neuronal arbor reconstruction. Extensive experiments on four neuronal imaging datasets, including two from BigNeuron and two public datasets, NeuroFly and CWMBS, demonstrate consistent improvements in reconstruction accuracy over SoTA methods, with average gains of 2.9% in Entire Structure Average, 2.8% in Different Structure Average, and 3.8% in Percentage of Different Structure. Code: https://github.com/yy0007/NeurINO.
Abstract:Monocular 3D object detection typically relies on pseudo-labeling techniques to reduce dependency on real-world annotations. Recent advances demonstrate that deterministic linguistic cues can serve as effective auxiliary weak supervision signals, providing complementary semantic context. However, hand-crafted textual descriptions struggle to capture the inherent visual diversity of individuals across scenes, limiting the model's ability to learn scene-aware representations. To address this challenge, we propose Visual-referred Probabilistic Prompt Learning (VirPro), an adaptive multi-modal pretraining paradigm that can be seamlessly integrated into diverse weakly supervised monocular 3D detection frameworks. Specifically, we generate a diverse set of learnable, instance-conditioned prompts across scenes and store them in an Adaptive Prompt Bank (APB). Subsequently, we introduce Multi-Gaussian Prompt Modeling (MGPM), which incorporates scene-based visual features into the corresponding textual embeddings, allowing the text prompts to express visual uncertainties. Then, from the fused vision-language embeddings, we decode a prompt-targeted Gaussian, from which we derive a unified object-level prompt embedding for each instance. RoI-level contrastive matching is employed to enforce modality alignment, bringing embeddings of co-occurring objects within the same scene closer in the latent space, thus enhancing semantic coherence. Extensive experiments on the KITTI benchmark demonstrate that integrating our pretraining paradigm consistently yields substantial performance gains, achieving up to a 4.8% average precision improvement than the baseline.
Abstract:Diffusion Transformers (DiTs) are a dominant backbone for high-fidelity text-to-image generation due to strong scalability and alignment at high resolutions. However, quadratic self-attention over dense spatial tokens leads to high inference latency and limits deployment. We observe that denoising is spatially non-uniform with respect to aesthetic descriptors in the prompt. Regions associated with aesthetic tokens receive concentrated cross-attention and show larger temporal variation, while low-affinity regions evolve smoothly with redundant computation. Based on this insight, we propose AccelAes, a training-free framework that accelerates DiTs through aesthetics-aware spatio-temporal reduction while improving perceptual aesthetics. AccelAes builds AesMask, a one-shot aesthetic focus mask derived from prompt semantics and cross-attention signals. When localized computation is feasible, SkipSparse reallocates computation and guidance to masked regions. We further reduce temporal redundancy using a lightweight step-level prediction cache that periodically replaces full Transformer evaluations. Experiments on representative DiT families show consistent acceleration and improved aesthetics-oriented quality. On Lumina-Next, AccelAes achieves a 2.11$\times$ speedup and improves ImageReward by +11.9% over the dense baseline. Code is available at https://github.com/xuanhuayin/AccelAes.
Abstract:Foundation vision models are increasingly adopted in medical image analysis. Due to domain shift, these pretrained models misalign with medical image segmentation needs without being fully fine-tuned or lightly adapted. We introduce GuiDINO, a framework that repositions native foundation model to acting as a visual guidance generator for downstream segmentation. GuiDINO extracts visual feature representation from DINOv3 and converts them into a spatial guide mask via a lightweight TokenBook mechanism, which aggregates token-prototype similarities. This guide mask gates feature activations in multiple segmentation backbones, thereby injecting foundation-model priors while preserving the inductive biases and efficiency of medical dedicated architectures. Training relies on a guide supervision objective loss that aligns the guide mask to ground-truth regions, optionally augmented by a boundary-focused hinge loss to sharpen fine structures. GuiDINO also supports parameter-efficient adaptation through LoRA on the DINOv3 guide backbone. Across diverse medical datasets and nnUNet-style inference, GuiDINO consistently improves segmentation quality and boundary robustness, suggesting a practical alternative to fine-tuning and offering a new perspective on how foundation models can best serve medical vision. Code is available at https://github.com/Hi-FishU/GuiDINO
Abstract:Robot motion distributions often exhibit multi-modality and require flexible generative models for accurate representation. Streaming Flow Policies (SFPs) have recently emerged as a powerful paradigm for generating robot trajectories by integrating learned velocity fields directly in action space, enabling smooth and reactive control. However, existing formulations lack mechanisms for adapting trajectories post-training to enforce safety and task-specific constraints. We propose Constraint-Aware Streaming Flow (CASF), a framework that augments streaming flow policies with constraint-dependent metrics that reshape the learned velocity field during execution. CASF models each constraint, defined in either the robot's workspace or configuration space, as a differentiable distance function that is converted into a local metric and pulled back into the robot's control space. Far from restricted regions, the resulting metric reduces to the identity; near constraint boundaries, it smoothly attenuates or redirects motion, effectively deforming the underlying flow to maintain safety. This allows trajectories to be adapted in real time, ensuring that robot actions respect joint limits, avoid collisions, and remain within feasible workspaces, while preserving the multi-modal and reactive properties of streaming flow policies. We demonstrate CASF in simulated and real-world manipulation tasks, showing that it produces constraint-satisfying trajectories that remain smooth, feasible, and dynamically consistent, outperforming standard post-hoc projection baselines.
Abstract:A substantial proportion (45\%) of maternal deaths, neonatal deaths, and stillbirths occur during the intrapartum phase, with a particularly high burden in low- and middle-income countries. Intrapartum biometry plays a critical role in monitoring labor progression; however, the routine use of ultrasound in resource-limited settings is hindered by a shortage of trained sonographers. To address this challenge, the Intrapartum Ultrasound Grand Challenge (IUGC), co-hosted with MICCAI 2024, was launched. The IUGC introduces a clinically oriented multi-task automatic measurement framework that integrates standard plane classification, fetal head-pubic symphysis segmentation, and biometry, enabling algorithms to exploit complementary task information for more accurate estimation. Furthermore, the challenge releases the largest multi-center intrapartum ultrasound video dataset to date, comprising 774 videos (68,106 frames) collected from three hospitals, providing a robust foundation for model training and evaluation. In this study, we present a comprehensive overview of the challenge design, review the submissions from eight participating teams, and analyze their methods from five perspectives: preprocessing, data augmentation, learning strategy, model architecture, and post-processing. In addition, we perform a systematic analysis of the benchmark results to identify key bottlenecks, explore potential solutions, and highlight open challenges for future research. Although encouraging performance has been achieved, our findings indicate that the field remains at an early stage, and further in-depth investigation is required before large-scale clinical deployment. All benchmark solutions and the complete dataset have been publicly released to facilitate reproducible research and promote continued advances in automatic intrapartum ultrasound biometry.
Abstract:Naturalistic fMRI characterizes the brain as a dynamic predictive engine driven by continuous sensory streams. However, modeling the causal forward evolution in realistic neural simulation is impeded by the timescale mismatch between multimodal inputs and the complex topology of cortical networks. To address these challenges, we introduce BrainVista, a multimodal autoregressive framework designed to model the causal evolution of brain states. BrainVista incorporates Network-wise Tokenizers to disentangle system-specific dynamics and a Spatial Mixer Head that captures inter-network information flow without compromising functional boundaries. Furthermore, we propose a novel Stimulus-to-Brain (S2B) masking mechanism to synchronize high-frequency sensory stimuli with hemodynamically filtered signals, enabling strict, history-only causal conditioning. We validate our framework on Algonauts 2025, CineBrain, and HAD, achieving state-of-the-art fMRI encoding performance. In long-horizon rollout settings, our model yields substantial improvements over baselines, increasing pattern correlation by 36.0\% and 33.3\% on relative to the strongest baseline Algonauts 2025 and CineBrain, respectively.